TABLE 3

Animal studies on antibody detection and isolation of ZIKV

YrCountryAnimal speciesNo. (%) of casesDiagnosisReference(s)
1947UgandaRhesus monkeys (Macaca mulatta)1d MIa 1
1947, 1948UgandaGrivets (Cercopithecus aethiops)1/13 (7.7)NT 117
Rhesus monkeys2/15 (13.3)
Redtail monkeys (Cercopithecus ascanius)0/2
    All3/30 (10)
1961, 1962Central African RepublicGrivets1/25 (4)HAc 122
1962–1964EthiopiaAbyssinian colobus (Colobus guereza)20/37 (54.1)HI 281
Baboons (Papio cynocephalus)3/7 (42.9)
Bats2/140 (1.4)
1967, 1968UgandaMonkeys139/204(68.1)HI 447
1967, 1968SenegalWild mammals1/100 (2.4)HI 110
1969Ugandab Redtail monkeys27/73 (37)HI 13
Mangabeys (Cercocebus)2/4 (50)
Mona monkeys (Cercopithecus mona)0/1 (0)
Colobus monkeys5/11 (45.5)
Other monkeys7/16 (43.7)
    All41/105 (39)
1969NigeriaMonkeys20/24 (83.3)HI 448
1969–1972NigeriaMonkeys immune to DENV-262/92 (67.4)NT 436
1972UgandaVervets2/3 (66.7)HI 126
Redtail monkeys7/18 (38.9)
    All9/21 (42.9)
1979, 1980GabonMonkeys9/34 (26.5)HI 280
1983PakistanRodents6/157(3.8)CF 121
Domestic animals2/172 (1.2)
1996, 1997BorneoOrangutans (Pongo)1/31 (3.22)NT 277, 278
    Semicaptive5/40(12.5)
    Free ranging6/71(8.5)
    All12/142 (8.5)
  • a MI, mouse inoculation.

  • b Kisubi and Bwamba.

  • c HA, hemagglutination assay.

  • d ZIKV MR prototype strain.