Table 3

Results from culture-based epidemiological studies of healthy skin

ReferenceNo. of patients/no. of positive cultures% of cultures positive for: Culture medium a Location(s)Description
M. globosaM. restrictaM. sympodialisM. furfurM. slooffiaeM. obtusaM. dermatis
353 123/107781721LNAIran7% mixed species (>2 species isolated); percentages correspond to avg of 3 samplings/patient
238 60/382832295114LNASouth KoreaVariations in isolation of species according to age; variation, yet not significant, in isolation of species according to body part; M. restricta on the forehead, M. sympodialis and M. globosa on the chest
164 160/599 (960 samples)2222124.520.52LNASouth Korea M. globosa and M. restricta were found more commonly in different age groups; M. restricta and M. globosa were found more commonly on the scalp; M. globosa and M. sympodialis were found more commonly on the trunk; mixed species were commonly isolated
254 40/32402017.52.5mDABosnia and HerzegovinaHealthy trunk skin of seborrheic dermatitis patients
255 90/8249375.5mDABosnia and HerzegovinaHealthy trunk skin of pityriasis versicolor patients, away from lesions; no association of the isolated species with sex, age, clinical appearance of pityriasis versicolor (hyper- or hypopigmented), duration of disease
135 245/1723215763LNACanadaDifferences in isolation rates of species between age groups and body locations were recorded; no mixed species isolated
138 20/1928647117.5LNACanadaCFU was equivalent to that associated with pityriasis versicolor and significantly more than those for psoriasis, seborrheic dermatitis, and atopic eczema
195 120 (600 samplings)/3934149642LNASouth Korea M. restricta was more common on the forehead and in younger age groups (<50 yr old); M. globosa was more frequent in patients aged >50 yr
311 100/6042325237DAIran
277 31/261269415LNASwedenMixed species were cultured in 11% of patients; healthy skin and seborrheic dermatitis skin were significantly more colonized than atopic eczema skin
228 105/524222162DAJapanTwo groups of healthy volunteers, i.e., 35 random volunteers and 73 medical school students; M. globosa, M. furfur, and M. sympodialis were isolated more frequently from scalp and face, but there was a low recovery rate for both groups studied; M. globosa and M. sympodialis were isolated from the trunks of healthy volunteers
275 35/114982320.52mDATunis3 sampling sites per patient, more than 1 isolate per patient; frequency of M. globosa on pityriasis versicolor skin was significantly higher than that on healthy skin
171 58/371950CHROMagar Malassezia JapanSampling of the external ear canal was performed; M. slooffiae was characterized as a specific isolate with increasing prevalence after the age of 30 yr
  • a NA, Leeming-Notman agar; mDA, modified Dixon's agar; DA, Dixon's agar.