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antibiotic resistance

  • Antimicrobial Resistance Surveillance in Low- and Middle-Income Countries: Progress and Challenges in Eight South Asian and Southeast Asian Countries
    Review
    Antimicrobial Resistance Surveillance in Low- and Middle-Income Countries: Progress and Challenges in Eight South Asian and Southeast Asian Countries

    Antimicrobial resistance (AMR) is a serious global health threat and is predicted to cause significant health and economic impacts, particularly in low- and middle-income countries (LMICs). AMR surveillance is critical in LMICs due to high burden of bacterial infections; however, conducting AMR surveillance in resource-limited settings is constrained by poorly functioning health systems, scarce financial resources, and lack of skilled...

    Sumanth Gandra, Gerardo Alvarez-Uria, Paul Turner, Jyoti Joshi, Direk Limmathurotsakul, H. Rogier van Doorn
  • Antimicrobial Resistance in ESKAPE Pathogens
    Review
    Antimicrobial Resistance in ESKAPE Pathogens

    Antimicrobial-resistant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae,...

    David M. P. De Oliveira, Brian M. Forde, Timothy J. Kidd, Patrick N. A. Harris, Mark A. Schembri, Scott A. Beatson, David L. Paterson, Mark J. Walker
  • Transferable Mechanisms of Quinolone Resistance from 1998 Onward
    Review
    Transferable Mechanisms of Quinolone Resistance from 1998 Onward

    While the description of resistance to quinolones is almost as old as these antimicrobial agents themselves, transferable mechanisms of quinolone resistance (TMQR) remained absent from the scenario for more than 36 years, appearing first as sporadic events and afterward as epidemics. In 1998, the first TMQR was soundly described, that is, QnrA.

    Joaquim Ruiz
  • The Use of Copper as an Antimicrobial Agent in Health Care, Including Obstetrics and Gynecology
    Review
    The Use of Copper as an Antimicrobial Agent in Health Care, Including Obstetrics and Gynecology

    Health care-associated infections (HAIs) are a global problem associated with significant morbidity and mortality. Controlling the spread of antimicrobial-resistant bacteria is a major public health challenge, and antimicrobial resistance has become one of the most important global problems in current times.

    Linda P. Arendsen, Ranee Thakar, Abdul H. Sultan
  • The Enterococcus: a Model of Adaptability to Its Environment
    Review
    The Enterococcus: a Model of Adaptability to Its Environment

    The genus Enterococcus comprises a ubiquitous group of Gram-positive bacteria that are of great relevance to human health for their role as major causative agents of health care-associated infections. The enterococci are resilient and versatile species able to survive under harsh conditions, making them well adapted to the health care environment.

    Mónica García-Solache, Louis B. Rice
  • Phage Therapy in the Postantibiotic Era
    Review
    Phage Therapy in the Postantibiotic Era

    Antibiotic resistance is arguably the biggest current threat to global health. An increasing number of infections are becoming harder or almost impossible to treat, carrying high morbidity, mortality, and financial cost.

    Fernando L. Gordillo Altamirano, Jeremy J. Barr
  • Review
    Mobile Genetic Elements Associated with Antimicrobial Resistance

    Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an increasing major health care problem around the world. It is now abundantly clear that both Gram-negative and Gram-positive bacteria are able to meet the evolutionary challenge of combating antimicrobial chemotherapy, often by acquiring preexisting resistance determinants from the bacterial gene pool.

    Sally R. Partridge, Stephen M. Kwong, Neville Firth, Slade O. Jensen
  • Review
    Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium) avidum, an Underrecognized Microorganism
    Stéphane Corvec
  • Review
    Recombinant Endolysins as Potential Therapeutics against Antibiotic-Resistant Staphylococcus aureus: Current Status of Research and Novel Delivery Strategies
    Hamed Haddad Kashani, Mathias Schmelcher, Hamed Sabzalipoor, Elahe Seyed Hosseini, Rezvan Moniri
  • Review
    Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns
    Deborah A. Williamson, Glen P. Carter, Benjamin P. Howden
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