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bacteria

  • State of the Art in the Culture of the Human Microbiota: New Interests and Strategies
    Review
    State of the Art in the Culture of the Human Microbiota: New Interests and Strategies

    The last 5 years have seen a turning point in the study of the gut microbiota with a rebirth of culture-dependent approaches to study the gut microbiota. High-throughput methods have been developed to study bacterial diversity with culture conditions aimed at mimicking the gut environment by using rich media such as YCFA (yeast extract, casein hydrolysate, fatty acids) and Gifu anaerobic medium in an anaerobic workstation, as well as...

    Maryam Tidjani Alou, Sabrina Naud, Saber Khelaifia, Marion Bonnet, Jean-Christophe Lagier, Didier Raoult
  • Performance and Application of 16S rRNA Gene Cycle Sequencing for Routine Identification of Bacteria in the Clinical Microbiology Laboratory
    Review
    Performance and Application of 16S rRNA Gene Cycle Sequencing for Routine Identification of Bacteria in the Clinical Microbiology Laboratory

    This review provides a state-of-the-art description of the performance of Sanger cycle sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical microbiology laboratory. A detailed description of the technology and current methodology is outlined with a major focus on proper data analyses and interpretation of sequences. The remainder of the article is focused on a comprehensive evaluation of the application...

    Deirdre L. Church, Lorenzo Cerutti, Antoine Gürtler, Thomas Griener, Adrian Zelazny, Stefan Emler
  • Microorganisms in the Placenta: Links to Early-Life Inflammation and Neurodevelopment in Children
    Review
    Microorganisms in the Placenta: Links to Early-Life Inflammation and Neurodevelopment in Children

    Prenatal exposure to various stressors can influence both early and later life childhood health. Microbial infection of the intrauterine environment, specifically within the placenta, has been associated with deleterious birth outcomes, such as preterm birth, as well as adverse neurological outcomes later in life.

    Martha Scott Tomlinson, Kun Lu, Jill R. Stewart, Carmen J. Marsit, T. Michael O’Shea, Rebecca C. Fry
  • Review
    The Role of BAFF System Molecules in Host Response to Pathogens
    Jiro Sakai, Mustafa Akkoyunlu
  • Review
    Chronic Rhinosinusitis and the Evolving Understanding of Microbial Ecology in Chronic Inflammatory Mucosal Disease
    Michael Hoggard, Brett Wagner Mackenzie, Ravi Jain, Michael W. Taylor, Kristi Biswas, Richard G. Douglas
  • Review
    Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis
    Matthijs C. Brouwer, Allan R. Tunkel, Diederik van de Beek
  • Review
    Mechanisms of Action and Clinical Application of Macrolides as Immunomodulatory Medications
    Soichiro Kanoh, Bruce K. Rubin
  • Review
    The Changing Microbial Epidemiology in Cystic Fibrosis
    John J. LiPuma
  • Review
    Three Decades of β-Lactamase Inhibitors
    Sarah M. Drawz, Robert A. Bonomo
  • Author's Correction
    Microbiology of Odontogenic Bacteremia: beyond Endocarditis
    N. B. Parahitiyawa, L. J. Jin, W. K. Leung, W. C. Yam, L. P. Samaranayake

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